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Wk 3 · 2026

Arizona Cardinals at San Francisco 49ers — Sun, Sep 27

Sun, Sep 27 · Levi's Stadium, Santa Clara, CA · Fox FINAL

Weather

No forecast yet. Forecasts reach about 16 days ahead, so this fills in nearer the game. A seasonal average printed here would look exactly like a forecast, which is why there is not one.
Arizona Cardinals
NFC West · 1-4
30
at
4:05pET
SF -7.5 · total 48.5 DraftKings opened -11.5 · 4 toward ARI
Ratings differential SF by 14.9
San Francisco 49ers
NFC West · 5-0
36

What is at stake

An NFC West game. These two play each other twice a season, home and away, and when the NFC West finishes level it is the head-to-head result and then the division record that separate them — before any of the rest. Division standings.

What the ratings imply

The differential above is arithmetic on two published numbers: The Gridiron King’s 2026 final efficiency ratings, plus 1.7 points of home field. It is not a projection, a value, an edge or a lean, and nothing on this site compares it with the betting line to tell you one is better. Until 2026 games are played it is last season’s measurement of two rosters that have been through a draft and a free-agency window since.

Efficiency · 2026 ratings

Cardinals: -6.5#31
Efficiency margin
49ers: +6.7#2
Cardinals: -1.2#23
Offense
49ers: +4.3#3
Cardinals: -5.3#32
Defense
49ers: +2.3#8
Cardinals: 20.9
Points / game
49ers: 25.7
Cardinals: 28.7
Points allowed / game
49ers: 21.8
Opponent-adjusted ratings from The Gridiron King’s 2026 final numbers. Bars share a scale within each row, so the two lengths are comparable; the brighter side is the better of the two, and a longer bar is the better number — including the rows where a lower figure is the good one. Pace is the exception: it is how fast a team plays, not how well, so neither side is lit and a longer bar there means only more plays.

Team stats

The box-score store these rows are built from has not been produced for this league yet, so no preview carries points and yards for and against. The form, trend and series blocks below are built from this site’s own files and are not affected.

Cardinals form

L 21-45vs DETL 24-36at NYGL 30-36at SFL 7-31vs SEAW 26-14at LAC
2026 season

49ers form

W 32-29at SEAW 24-14vs DENW 36-30vs ARIW 35-13vs MIAW 27-7at LAR
2026 season

Cardinals this season

Straight up1-4 · 20% (5 games)
Against the spread2-3 · 40% (5 games)
Over / under3-2 · 60% (5 games)

49ers this season

Straight up5-0 · 100% (5 games)
Against the spread4-1 · 80% (5 games)
Over / under3-2 · 60% (5 games)
Lines are captured from ESPN's board before kickoff and locked at kickoff, so an in-play price cannot overwrite the number a game is graded against.

Common opponents · 10

OpponentCardinals49ers
Chargers
AFC
at W 26-14 previewat Wk 15 · scheduled preview
Seahawks
NFC
vs L 7-31 previewat W 32-29 preview
Giants
NFC
at L 24-36 previewat Wk 13 · scheduled preview
Rams
NFC
at Wk 6 · scheduled previewN W 27-7 preview
Broncos
AFC
vs Wk 7 · scheduled previewvs W 24-14 preview
Cowboys
NFC
at Wk 8 · scheduled previewat Wk 10 · scheduled preview
Chiefs
AFC
at Wk 11 · scheduled previewat Wk 16 · scheduled preview
Commanders
NFC
vs Wk 12 · scheduled previewvs Wk 6 · scheduled preview
Eagles
NFC
vs Wk 13 · scheduled previewvs Wk 17 · scheduled preview
Raiders
AFC
vs Wk 17 · scheduled previewvs Wk 9 · scheduled preview
Open these two in the comparison tool for every shared and unshared opponent.

Series history · 2006–2026

Since 2006, 49ers leads 22–19 · 49ers has won the last 3
41 meetings in 2006–2026 · average margin 2.7 points toward 49ers
Yr DateResultSiteWon
20262026-09-27Cardinals 30 — 36 49ersat SF49ers
20252025-11-1649ers 41 — 22 Cardinalsat ARI49ers
20252025-09-21Cardinals 15 — 16 49ersat SF49ers
20242025-01-0549ers 24 — 47 Cardinalsat ARICardinals
20242024-10-06Cardinals 24 — 23 49ersat SFCardinals
20232023-12-1749ers 45 — 29 Cardinalsat ARI49ers
20232023-10-01Cardinals 16 — 35 49ersat SF49ers
20222023-01-08Cardinals 13 — 38 49ersat SF49ers
20222022-11-2149ers 38 — 10 Cardinalsneutral49ers
20212021-11-07Cardinals 31 — 17 49ersat SFCardinals
20212021-10-1049ers 10 — 17 Cardinalsat ARICardinals
20202020-12-2649ers 20 — 12 Cardinalsat ARI49ers
20202020-09-13Cardinals 24 — 20 49ersat SFCardinals
20192019-11-17Cardinals 26 — 36 49ersat SF49ers
20192019-10-3149ers 28 — 25 Cardinalsat ARI49ers
20182018-10-2849ers 15 — 18 Cardinalsat ARICardinals
20182018-10-07Cardinals 28 — 18 49ersat SFCardinals
20172017-11-05Cardinals 20 — 10 49ersat SFCardinals
20172017-10-0149ers 15 — 18 Cardinalsat ARICardinals
20162016-11-1349ers 20 — 23 Cardinalsat ARICardinals
20162016-10-06Cardinals 33 — 21 49ersat SFCardinals
20152015-11-29Cardinals 19 — 13 49ersat SFCardinals
20152015-09-2749ers 7 — 47 Cardinalsat ARICardinals
20142014-12-28Cardinals 17 — 20 49ersat SF49ers
20142014-09-2149ers 14 — 23 Cardinalsat ARICardinals
20132013-12-2949ers 23 — 20 Cardinalsat ARI49ers
20132013-10-13Cardinals 20 — 32 49ersat SF49ers
20122012-12-30Cardinals 13 — 27 49ersat SF49ers
20122012-10-2949ers 24 — 3 Cardinalsat ARI49ers
20112011-12-1149ers 19 — 21 Cardinalsat ARICardinals
20112011-11-20Cardinals 7 — 23 49ersat SF49ers
20102011-01-02Cardinals 7 — 38 49ersat SF49ers
20102010-11-2949ers 27 — 6 Cardinalsat ARI49ers
20092009-12-14Cardinals 9 — 24 49ersat SF49ers
20092009-09-1349ers 20 — 16 Cardinalsat ARI49ers
20082008-11-1049ers 24 — 29 Cardinalsat ARICardinals
20082008-09-07Cardinals 23 — 13 49ersat SFCardinals
20072007-11-2549ers 37 — 31 Cardinalsat ARI49ers
20072007-09-10Cardinals 17 — 20 49ersat SF49ers
20062006-12-24Cardinals 26 — 20 49ersat SFCardinals
20062006-09-1049ers 27 — 34 Cardinalsat ARICardinals

Cardinals leaders 2026 regular season

PassingJacoby Brissett QB #7103/152, 818 YDS, 6 TD, 4 INT
RushingJeremiyah Love RB #455 CAR, 223 YDS, 1 TD
Tyler Allgeier RB #2232 CAR, 112 YDS, 1 TD
Jacoby Brissett QB #715 CAR, 43 YDS, 1 TD
ReceivingMichael Wilson WR #1425 REC, 258 YDS, 1 TD
Trey McBride TE #8533 REC, 242 YDS, 2 TD
Kendrick Bourne WR #1712 REC, 108 YDS
Marvin Harrison Jr. WR #185 REC, 85 YDS, 1 TD
Defense
TacklesJack Gibbens LB #5032
Mack Wilson Sr. LB #128
Budda Baker S #325
SacksBudda Baker S #31.5
Josh Sweat LB #101
Zaven Collins LB #251
InterceptionsBudda Baker S #31
Andrew Wingard S #271
Denzel Burke CB #291
full roster and per-player history

49ers leaders 2026 regular season

PassingBrock Purdy QB #1379/113, 1007 YDS, 11 TD, 1 INT
RushingChristian McCaffrey RB #2350 CAR, 218 YDS, 4 TD
Brock Purdy QB #1320 CAR, 122 YDS, 1 TD
Kaelon Black RB #2631 CAR, 120 YDS
ReceivingGeorge Kittle TE #8516 REC, 244 YDS, 4 TD
Mike Evans WR #517 REC, 213 YDS, 2 TD
Deebo Samuel Sr. WR #1914 REC, 185 YDS, 3 TD
Christian McCaffrey RB #2316 REC, 122 YDS
Defense
TacklesFred Warner LB #5440
Dre Greenlaw LB #5734
Ji'Ayir Brown S #2728
SacksKeion White DE #562
Ogbo Okoronkwo LB #591
Romello Height DE #941
InterceptionsRenardo Green CB #01
full roster and per-player history
These are regular-season totals for the season named on each card — the players who led that team that year, taken from ESPN's team leaders. That list is keyed to the season, not to today's roster, so a leader who has since signed elsewhere, been traded or retired still appears against the year he earned it; the roster pages and the depth chart on each team page are where the current squad is. A team switches to this season's numbers once it has played a game.