| Player | Pos | Team |
|---|---|---|
| Bryson Eason | DT | San Francisco 49ers |
| Deven Eastern | DT | Seattle Seahawks |
| Arnold Ebiketie | LB | Philadelphia Eagles |
| Justin Eboigbe | DT | Los Angeles Chargers |
| Samson Ebukam | DE | Atlanta Falcons |
| Brandin Echols | CB | Pittsburgh Steelers |
| Power Echols | LB | Seattle Seahawks |
| Ryan Eckley | P | Baltimore Ravens |
| Christopher Edmonds | S | Cleveland Browns |
| Tremaine Edmunds | LB | New York Giants |
| Chuma Edoga | G | Jacksonville Jaguars |
| David Edwards | G | New Orleans Saints |
| Donovan Edwards | RB | Miami Dolphins |
| Johnathan Edwards | CB | Indianapolis Colts |
| T.J. Edwards | LB | Chicago Bears |
| TeRah Edwards | DT | Los Angeles Chargers |
| Tru Edwards | WR | Los Angeles Rams |
| Emeka Egbuka | WR | Tampa Bay Buccaneers |
| Kingsley Eguakun | C | Cleveland Browns |
| Sam Ehlinger | QB | Denver Broncos |
| Tommy Eichenberg | LB | Las Vegas Raiders |
| Milo Eifler | LB | Tennessee Titans |
| Paschal Ekeji | DE | New York Jets |
| Ikem Ekwonu | OT | Carolina Panthers |
| Kaiir Elam | CB | Kansas City Chiefs |
| Kaleb Elarms-Orr | LB | Buffalo Bills |
| DeShon Elliott | S | Pittsburgh Steelers |
| Jake Elliott | PK | Philadelphia Eagles |
| Jordan Elliott | DT | Tennessee Titans |
| Keyshaun Elliott | LB | Chicago Bears |
| Christian Elliss | LB | New England Patriots |
| Jonah Elliss | LB | Denver Broncos |
| Kaden Elliss | LB | New Orleans Saints |
| Jermaine Eluemunor | OT | New York Giants |
| Nick Emmanwori | S | Seattle Seahawks |
| Kingsley Enagbare | LB | New York Jets |
| Jack Endries | TE | Cincinnati Bengals |
| Evan Engram | TE | Denver Broncos |
| AJ Epenesa | DE | Philadelphia Eagles |
| Marcus Epps | S | Philadelphia Eagles |
| Aireontae Ersery | OT | Houston Texans |
| James Ester | G | Miami Dolphins |
| Audric Estime | RB | New Orleans Saints |
| Trevor Etienne | RB | Carolina Panthers |
| Akayleb Evans | CB | Carolina Panthers |
| Ethan Evans | P | Los Angeles Rams |
| Mike Evans | WR | San Francisco 49ers |
| Mitchell Evans | TE | Carolina Panthers |
| Nate Evans | CB | Cleveland Browns |
| Omari Evans | WR | Kansas City Chiefs |
| Daylen Everette | CB | Pittsburgh Steelers |
| Quinn Ewers | QB | Miami Dolphins |
| Donovan Ezeiruaku | LB | Dallas Cowboys |
| Joshua Ezeudu | G | Kansas City Chiefs |
| Erik Ezukanma | WR | Philadelphia Eagles |